History
Since its founding in 1997, the International Vaccine Institute has been at the forefront of global vaccine research, development, and delivery, driven by a mission to protect the world’s most vulnerable people. Our journey reflects a deep commitment to advancing equitable access to vaccines.
- Oct 1996
- The Republic of Korea and United Nations Development Programme sign the IVI Establishment Agreement at the UN headquarters in New York City.
- Oct 1997
- IVI is officially established under the Vienna Convention as an independent and autonomous international organization.
- Jul 1999
- Dr. John Clemens becomes the first Director General at the IVI interim office at Seoul National University.
- Jan 2000
- Bill and Melinda Gates Foundation awards IVI its first grant, the Diseases of the Most Impoverished Program, to generate scientific evidence on the burden of cholera, typhoid fever, and shigellosis.
- Jun 2003
- IVI’s new headquarters building opens, donated by the Government of the Republic of Korea.
- Jul 2006
- Bill and Melinda Gates Foundation awards a grant to launch the Cholera Vaccine Initiative to develop and introduce new oral cholera vaccines.
- Oct 2007
- Bill and Melinda Gates Foundation awards a grant to launch the Vi-based Vaccines for Asia Initiative to develop and introduce new and improved typhoid vaccines.
- Feb 2009
- The oral cholera vaccine developed through IVI and produced by Shantha Biotechnics, Shanchol™, is licensed in India – the first vaccine developed through IVI to achieve licensure.
- Sep 2011
- World Health Organization prequalifies the IVI-developed oral cholera vaccine Shanchol™.
- Dec 2011
- Dr. Christian Loucq becomes IVI’s second Director General.
- Oct 2013
- Results from a Phase III trial follow-up on the oral cholera vaccine, Shanchol™, show protective efficacy of about 65% over five years.
- Jan 2014
- IVI partners with Incepta Vaccine Ltd. of Bangladesh, transferring technology for an oral cholera vaccine then for a typhoid conjugate vaccine.
- Feb 2015
- Euvichol® receives licensure and is the first cholera vaccine developed and produced in the Republic of Korea for use in low- and middle-income countries.
- Mar 2015
- IVI, with the Republic of Korea’s Ministry of Foreign Affairs, Malawi’s Ministry of Health, and the World Health Organization, conduct emergency cholera vaccinations in flood-stricken Malawi, immunizing more than 130,000 people.
- Jun 2015
- Dr. Jerome Kim becomes IVI’s third Director General.
- Aug 2017
- World Health Organization prequalifies the oral cholera vaccine Euvichol-Plus®.
- Aug 2018
- An IVI oral cholera vaccine campaign in Mozambique vaccinates nearly 200,000 people against cholera.
- Oct 2018
- IVI hosts its first State Forum, highlighting the importance of vaccine research and development in global health diplomacy.
- Mar 2019
- IVI launches the Typhoid Conjugate Vaccine Introduction in Africa project to demonstrate the effectiveness of typhoid conjugate vaccines in four countries.
- 2019
- IVI launches the Strep A Global Vaccine Consortium with Murdoch Children’s Research Institute to advance the development of group A Strep vaccines.
- 2020
- In response to the COVID-19 pandemic, IVI joins forces with over 30 partners to support the preclinical and clinical development of COVID-19 vaccine candidates.
- 2020
- Bangladesh licenses Incepta’s Cholvax® oral cholera vaccine, the first domestically manufactured cholera vaccine in Bangladesh, made possible by an IVI technology transfer.
- Feb 2022
- The Korean Ministry of Health and Welfare designates IVI the operator of the Global Training Hub for Biomanufacturing, a program supported by the World Health Organization to increase vaccine manufacturing capacity in low- and middle-income countries.
- Apr 2022
- IVI and SK bioscience launch the annual IVI-SK bioscience Park MahnHoon Award for individuals or organizations making outstanding contributions in vaccines for global health.
- Sept 2022
- IVI establishes its Europe Regional Office in Stockholm, Sweden and an IVI Country Office in Vienna, Austria.
- Oct 2022
- IVI launches its Global Advisory Group of Experts to advance diplomatic and global health efforts.
- Oct 2022
- IVI celebrates its 25th anniversary, presenting the inaugural IVI Founders Medal to Prof. Seung Il Shin, Prof. Barry Bloom, Prof. Wan Kyoo Cho, and Prof. Sang-Dai Park.
- 2022
- IVI leads phase III clinical trials of a COVID-19 vaccine developed by SK bioscience at sites in six countries.
- May 2023
- IVI gains observer status at the World Health Assembly.
- Oct 2023
- IVI convenes the inaugural Global Council meeting in Seoul, establishing a new representative body for all IVI States Parties.
- 2023
- IVI establishes an antimicrobial resistance department to increase research on the impact of vaccination on antimicrobial use, consumption, and resistance.
- May 2024
- IVI forms a global research consortium supported by the Coalition for Epidemic Preparedness Innovations to develop a broadly protective coronavirus vaccine.
- Nov 2024
- IVI establishes its Africa Regional Office in Kigali, Rwanda.

