Press Releases

Press Releases

International Vaccine Institute and Technical University of Denmark to strengthen external quality assurance in the face of rising antimicrobial resistance in Asia

IVI and Sweden renew partnership to accelerate vaccines for global public health

IVI to lead critical standard reagents availability for oral cholera vaccine manufacturing to ensure their uniform efficacy and help meet global demand

IVI appoints three new members to its Board of Trustees

IVI to Accelerate Efforts in iNTS Vaccine Development

IVI acquires GCLP certification from Korean Ministry of Food and Drug Safety

IVI Awarded $4.5 Million Grant to Increase Accessibility of Oral Cholera Vaccine

IVI Discusses Expanding Support for Global Collaboration on Vaccine R&D and Delivery with Top Foreign Diplomats in Seoul

IVI-led Consortium Awarded Fleming Fund Regional Grant to Improve Data Sharing in Fight against Antimicrobial Resistance

IVI to help developing countries tackle the spread of infectious diseases by building capacity through vaccinology training in Seoul

IVI acquires supplemental funding for Severe Typhoid in Africa Program (SETA Plus)

IVI Director General Dr. Jerome Kim to join the Human Vaccines Project’s Efforts as One of Four Distinguished Global Leaders to Decode the Human Immune System

Prof. Young Chul Sung, biotech leader, personally donates US$8.4 million to IVI

New push to develop world’s first vaccine against the deadly Strep A bacteria killing hundreds of thousand

IVI-led CAPTURA consortium wins Fleming Fund award for work on antimicrobial resistance (AMR) data across Asia

IVI receives $15.7 million grant to conduct phase III trials of new Vi-DT typhoid conjugate vaccine manufactured by SK bioscience of Korea

‘IVI Forum for Enhancement of Cooperation’ hosted jointly by the Korean Parliamentary Forum for Global Health, and KCDC under MOHW

Vaccine study confirms sensitivity of cholera test

Korean Pediatric Association, IVI, KSC exchange MOU

IVI receives $3.2 million grant to support TCV effectiveness studies in West Africa

CEPI partners with IVI to accelerate development of vaccines against emerging global health threats

Henry Lau joins IVI as Goodwill Ambassador

Nature Communications study addresses MDR typhoid

THSTI, IVI held joint symposium on Nov. 22

‘The Euvichol story’ published in Vaccine

IVI accelerates development of MERS vaccine

IVI’s 18th Vaccinology Course gathers 120 international participants from 19 countries in Seoul September 3-7

KOICA, IVI team up with Mozambican MoH and INS, partners to vaccinate 190,000 people against cholera

IVI acquires $5 million grant to support process development, scale up of typhoid conjugate vaccine with SK Bioscience


NIBSC, IVI jointly organize meeting on cholera vaccine standardization

2018-06-21 00:55
In May representatives from academia, industry, regulatory agencies and the World Health Organization joined together to share their experiences with batch release testing of oral cholera vaccines.

Organized in Seoul, South Korea on May 17-18 by colleagues at the International Vaccine Institute (IVI) and NIBSC, and supported by the Bill and Melinda Gates foundation, the Meeting on International Standards for Oral Cholera vaccines saw experts review potency tests used for the batch release.

One of the key topics was the need for standards to harmonize the LPS inhibition ELISA, an in vitro assay commonly used for batch release, across manufacturers and regulatory agencies.

Delegates at the meeting on International Standards for Oral Cholera Vaccines in Seoul, South Korea. Image Courtesy of the International Vaccine Institute (IVI)

During the meeting attendees agreed on the importance of developing reference reagents for coating antigens and primary detection antibodies used in this ELISA, as well as a reference vaccine. Delegates highlighted the need for these reagents to be tested by a wide range of laboratories in an international collaborative study.

The proposed reference reagents will be filled and freeze-dried at the NIBSC specialized manufacturing facility. Pending financial support, materials should be available within four to five years. The standards will support delivery of oral cholera vaccines for public health campaigns in low and middle income countries and the management of the global WHO stockpile.

Dr. Viliam Pavliak, Head of Vaccine Process Development at IVI and organizer of the meeting commented: “The meeting provided us with important information on the ELISA assay formats used by various manufacturers and regulators to support batch release of oral cholera vaccines. Participants agreed on development of the set of reference reagents for this assay to help accelerate the batch release of this life saving vaccine.”

A full report from the meeting is due to be submitted for publication in a peer reviewed journal.


About International Vaccine Institute (IVI)

The International Vaccine Institute (IVI) is the world’s only international organization devoted exclusively to developing and introducing new and improved vaccines to protect the world’s poorest people, especially children in developing countries. Established in 1997, IVI operates as an independent international organization under a treaty signed by 35 countries and the World Health Organization. The Institute conducts research in nearly 30 countries throughout Asia, Africa and Latin America on vaccines against enteric and diarrheal infections such as cholera and typhoid, Japanese encephalitis, MERS-CoV, tuberculosis, and dengue fever; and develops new and improved vaccines at its headquarters in Seoul, Republic of Korea. For more information, visit


The National Institute for Biological Standards and Control (NIBSC) is a world leader in assuring the quality of biological medicines through product testing, developing standards and reference materials and carrying out applied research. NIBSC is a center of the Medicines and Healthcare products Regulatory Agency which also includes CPRD and MHRA. The Medicines and Healthcare products Regulatory Agency is an executive agency of the Department of Health.