Alarmingly rapid spread of dengue in the world - WHO report
According to the World Health Organization’s Second Report on NTDS: Sustaining the Drive to Overcome the Global Impact of Neglected Tropical Diseases, dengue is estimated to be the world's most rapidly emerging vector-borne viral disease. IVI estimates that dengue is also the world's most rapidly spreading major tropical disease.
The implications are significant. In an age when some diseases, such as malaria and hepatitis B, are receding, dengue is exploding with a 30-fold increase in incidence over the last 50 years worldwide [1-2]. It is increasingly affecting travelers from developed countries who go to endemic countries and could pose as a pandemic threat . A recent update on the estimation of the disease burden reported 128 countries to be at risk with 3.97 billion people affected globally . The disease, economic and social burdens of dengue are increasingly presenting major challenges to governments of endemic countries [5-6]. According to the WHO report, “The world needs to change its reactive approach and implement sustainable preventive measures.”
IVI welcomes the WHO report as IVI and its partners of the Dengue Vaccine Initiative have been working hard in the fight against dengue. Recognizing that vaccines are the most promising way to confront the dengue problem, IVI and DVI are creating an environment to accelerate the development and introduction of dengue vaccines.
1 WHO. Sustaining the drive to overcome the global impact of neglected tropical diseases. Second WHO report on neglected tropical diseases. 2013
2 Kyle JL, Harris E. Global spread and persistence of dengue. Annu Rev Microbiol. 2008;62:71-92. 3 Tatem, A. J., Hay, S. I. & Rogers, D. J. Global traffic and disease vector dispersal. Proc. Natl. Acad. Sci. U. S. A. 103, 6242-6247 (2006).
4 Brady OJ, Gething PW, Bhatt S, Messina JP, Brownstein JS, Hoen AG, Moyes CL, Farlow AW, Scott TW, Hay SI. Refining the global spatial limits of dengue virus transmission by evidence-based consensus. PLoS Negl Trop Dis. 2012;6(8):e1760. doi: 10.1371/journal.pntd.0001760. Epub 2012 Aug 7.
5 Gubler DJ. The economic burden of dengue. Am J Trop Med Hyg. 2012 May;86(5):743-4.
6 Gubler DJ. Epidemic dengue/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century. Trends Microbiol. 2002 Feb; 10(2):100-3.