2020 was an unprecedented year in global health. A novel virus spread to all corners of the world, devastating people’s lives, economies, and ways of life, and the scientific community responded with agility and partnership that will inspire vaccine research and development for years to come. We’re grateful to our global collaborators, supporters, and friends for working with us to advance IVI’s mission to discover, develop, and deliver safe, effective, and affordable vaccines for global health—a mission that feels more urgent than ever and will continue to drive our work in the new year.